Snapshot A 55-year-old man presents to his primary care physician for evaluation of his peripheral neuropathy. He otherwise feels well. Physical examination is notable for decreased sensation to pinprick in the bilateral lower extremities. Laboratory studies were notable for an M spike in protein electrophoresis of the blood and M protein at a concentration of 2 g/dL in the serum. He undergoes a bone marrow biopsy, which demonstrates 4% monoclonal plasma cells. Introduction Overview login to view 8 more bullets Epidemiology Incidence login to view 1 more bullet Risk factors login to view 3 more bullets ETIOLOGY Pathophysiology login to view 2 more bullets Presentation Symptoms/physical exam login to view 2 more bullets Studies Serum labs login to view 3 more bullets Invasive studies login to view 2 more bullets Differential Multple myeloma login to view 3 more bullets Treatment Lifestyle login to view 4 more bullets Complications Multiple myeloma Other lymphoproliferative disorders Prognosis Associated with lower survival than the general population login to view 1 more bullet