Snapshot A 51-year-old woman presents to her primary care physician with a lump in her right breast. She says it has been there for around a year. Mammography shows a dominant mass with an irregular fibrotically stranded boundary, with some of the strands seeming to extend toward the nipple. A core biopsy was done and showed the following histology. Introduction Overview login to view 4 more bullets Epidemiology Demographics login to view 1 more bullet Incidence login to view 2 more bullets Risk factors login to view 7 more bullets ETIOLOGY Genetics login to view 5 more bullets Presentation Symptoms login to view 4 more bullets Physical exam login to view 12 more bullets See Breast Cancer General Imaging Mammography login to view 5 more bullets Core or excisional biopsy login to view 9 more bullets Stage with TNM Staging System Studies Serum calcium level login to view 1 more bullet Alkaline phosphatase login to view 1 more bullet Hormone receptor tests login to view 3 more bullets Differential Invasive lobular carcinoma login to view 6 more bullets Ductal carcinoma in situ (DCIS) login to view 2 more bullets Treatment Medical login to view 18 more bullets Surgical login to view 18 more bullets Complications Metastasis Recurrence login to view 1 more bullet Death Prognosis Tumor size is most important prognostic factor Metastasis associated with poorer prognosis Second most common cause of cancer-related death in women