Snapshot A 75-year-old man presents to his primary care physician with complaint of feeling excessive fatigue in the past few months. He notices that he feels a tightness in his chest and shortness of breath as he goes about his day, though the discomfort is not exacerbated by deep breathing. He has lost 20 pounds in the past half year despite maintaining the same diet and having a decreased level of activity due to his fatigue. A chest radiograph is obtained and is shown in the image. Introduction Overview login to view 1 more bullet Epidemiology Incidence login to view 1 more bullet Demographics login to view 2 more bullets Risk factors login to view 5 more bullets Presentation Symptoms login to view 6 more bullets Physical exam login to view 1 more bullet Imaging Chest radiograph login to view 4 more bullets CT or MRI of chest login to view 2 more bullets Studies Thoracentesis login to view 1 more bullet Pleural biopsy login to view 7 more bullets Differential Non-small cell lung cancer login to view 2 more bullets Small cell lung cancer login to view 2 more bullets Treatment Medical login to view 6 more bullets Surgical login to view 2 more bullets Prognosis Median survival for malignant mesothelioma is 11 months login to view 1 more bullet