Snapshot A 65-year-old man presents to his physician's office after noticing blood in his urine earlier this morning. This has never happened before and he denies any new medications or prior infection. He also reports to having flank pain for the past few weeks. Medical history is significant for hypertension. He has a 40 pack-year smoking history. On physical examination there is a firm, nontender, and homogeneous mass in the right flank. Computerized tomography (CT) scan of the abdomen is shown. Introduction Clinical definition login to view 1 more bullet Epidemiology Incidence login to view 6 more bullets Demographics login to view 2 more bullets Risk factors login to view 5 more bullets ETIOLOGY Pathogenesis login to view 1 more bullet Associated conditions login to view 5 more bullets Presentation Symptoms login to view 3 more bullets Physical exam login to view 12 more bullets Imaging CT scan login to view 9 more bullets Studies Histology login to view 2 more bullets Differential Benign kidney tumors such as login to view 1 more bullet Urothelial carcinoma Lymphoma Treatment Medical login to view 5 more bullets Surgical login to view 4 more bullets Complications Paraneoplastic syndromes resulting in login to view 3 more bullets Prognosis Poorer prognosis login to view 5 more bullets