Snapshot A 47-year-old man presents to the emergency department complaining of a headache. His symptoms have been progressively worsening over the course of week. He does not have a past medical history of headaches and has noticed some weakness in his left upper extremity. Physical examination is notable for 4/5 power throughout the left upper extremity. MRI brain with gadolinium demonstrates a white matter mass lesion with patchy enhancement. Neurosurgery is consulted for surgical resection. Introduction Definition login to view 2 more bullets ETIOLOGY Pathophysiology login to view 1 more bullet Epidemiology Demographics login to view 1 more bullet Presentation Symptoms/physical exam login to view 4 more bullets Imaging MRI brain with and without contrast login to view 6 more bullets Studies Histopathology and molecular testing login to view 8 more bullets Differential Other malignant brain neoplasm login to view 3 more bullets Treatment Surgical login to view 5 more bullets Complications Seizures Neurological deficits Prognosis Poor