Snapshot An 13-year-old boy presents to his pediatrician for right distal thigh pain. He has been having pain in this area for the past few months, has progressively worsened, and persists in the night. Physical examination is notable for tenderness upon palpation above the right knee. A radiograph of the distal thigh demonstrates a sunburst pattern and Codman triangle. Introduction Overview login to view 2 more bullets Epidemiology Incidence login to view 2 more bullets Risk factors login to view 5 more bullets ETIOLOGY Pathophysiology login to view 1 more bullet Associated conditions login to view 3 more bullets Symptoms Symptoms login to view 9 more bullets Physical exam login to view 1 more bullet Imaging Radiography login to view 9 more bullets MRI login to view 3 more bullets Radionuclide bone scan login to view 2 more bullets Studies Invasive studies login to view 3 more bullets Histology login to view 2 more bullets Differential Ewing sarcoma login to view 3 more bullets Treatment Treatment consists of surgical resection (even amputation), chemotherapy, and radiation therapy login to view 1 more bullet Complications Metastasis Amputation Prognosis Prognostic variable login to view 7 more bullets