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A 61-year-old woman presents to her primary care physician with complaints of increasing abdominal distension over the last 3 months, as well as more recent onset of early satiety and constipation over the last several weeks. She has a past medical history of obesity and diabetes. She states she feels more distended in her abdomen but has lost 10 pounds this past month. The patient has a 20 pack-year smoking history and was an alcoholic with her last drink 7 years ago. Her father died of colon cancer at the age of 62 and her mother died of breast cancer at the age of 45. She takes naproxen and ibuprofen for joint and back pain. Her temperature is 97.4°F (36.3°C), blood pressure is 120/81 mmHg, pulse is 83/min, respirations are 15/min, and oxygen saturation is 99% on room air. Physical exam is notable for an elderly woman who has muscle wasting and a distended abdomen. Ultrasound is performed as seen in Figure A of the left lower quadrant of the abdomen. Which of the following is the most likely diagnosis?
Non-alcoholic fatty liver disease
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A 58-year-old female presents to her primary care physician with complaints of fatigue, shortness of breath, weight gain, and increased abdominal bloating over the last month. She also reports intermittent chest pains, and she has had trouble buttoning her pants, which have been feeling abnormally tight, over the last several weeks. Her vital signs are as follows: T 37.0, HR 104, BP 128/75, RR 18, SpO2 95%. Physical examination is significant for the following findings: dullness to percussion and decreased breath sounds of the right middle and lower lobes; palpation of a solid, 8 cm unilateral right-sided pelvic mass; shifting dullness on percussion of the abdomen; visible fluid-wave. A chest radiograph is performed and shows a right-sided pleural effusion. A CT scan of the abdomen-pelvis is obtained and shown in Figure A. Which of the following ovarian tumors is most commonly associated with this patient's presentation?
Endodermal sinus tumor
A 38-year-old G4P3 African American woman presents to her OBGYN for a routine prenatal check up. She denies any problems, except that she's noticed increased acne and dark hair on her face lately. She also thinks her hair might be falling out around her temples. Her physical exam is notable for a gravid uterus and possible left ovarian mass palpated on bimaual exam. Transvaginal ultrasound reveals bilateral solid ovarian masses as seen in Figure A (R adnexa only shown). What is the most appropriate next step in treatment?
Delayed chemotherapy following delivery
Delayed surgery following delivery
Reassurance; repeat ultrasound following delivery