Snapshot A 72-year-old man presents to his primary care physician with generalized fatigue and mild abdominal pain. He has had a 25-pound weight loss over the course of 2 months. He has a past medical history of alcohol use disorder complicated by chronic pancreatitis. He also has been smoking 1 pack of cigarettes for the past 40 years. Physical examination is notable for scleral icterus and abdominal tenderness to palpation in the epigastric region. An abdominal ultrasound demonsrates a pancreatic mass compressing the biliary system. CT abdomen with and without contrast demonstrates a mass at the head of the pancreas. Introduction Overview login to view 7 more bullets Epidemiology Incidence login to view 1 more bullet Demographics login to view 1 more bullet Risk factors login to view 5 more bullets Etiology Likely from accumulation of various genetic mutations login to view 1 more bullet Pathogenesis login to view 2 more bullets Presentation Symptoms login to view 5 more bullets Physical exam login to view 4 more bullets Imaging Abdominal ultrasound login to view 3 more bullets Abdominal CT scan login to view 3 more bullets Endoscopic retrograde cholangiopancreatography (ERCP) login to view 3 more bullets Endoscopic ultrasonography login to view 3 more bullets Studies Serum labs login to view 5 more bullets Differential Acute pancreatitis login to view 2 more bullets Gastric cancer login to view 2 more bullets Treatment Treatment depends on the stage of the pancreatic cancer Surgical login to view 3 more bullets Prognosis Very poor prognosis