Snapshot A 43-year-old man presents to his primary care physican for a pigmented lesion on his right forearm. He has had multiple sunburns in the past and works as a farmer, spending most of the day outside. Physical examination is notable for a 7-mm hyperpigmented lesion that is asymmetric with irregular borders and color variation. He undergoes an excisional biopsy, which demonstrates larger than normal melanocytes of various sizes with large hyperchromatic nuclei in the lower epidermis and dermis. Introduction Overview login to view 16 more bullets Epidemiology Incidence login to view 1 more bullet Risk factors login to view 5 more bullets ETIOLOGY Pathophysiology login to view 5 more bullets Presentation Physical exam login to view 7 more bullets Studies Serum labs login to view 1 more bullet Invasive studies login to view 13 more bullets Differential Actinic keratosis login to view 3 more bullets Basal cell carcinoma login to view 4 more bullets Treatment Medical login to view 4 more bullets Surgical login to view 3 more bullets Complications Metastatic melanoma login to view 5 more bullets Prognosis Prognostic favorable login to view 4 more bullets