Snapshot A 35-year-old man presents to the emergency department with cough and progressively worsening shortness of breath. He recently returned from a medical mission in East Asia approximately 10 days ago, where he was managing multiple patients with respiratory symptoms. His temperature is 101°F (38.3°C), blood pressure is 135/85 mmHg, pulse is 100/min, and respirations are 20/min with an oxygen saturation of 92%. A CT of the chest demonstrates ground glass opacities, fine reticular opacities, and vascular thickening. SUMMARY Condition is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) login to view 2 more bullets Diagnosed by a positive nasal swab Treatment is observation and isolation for mild cases, while severe cases require hospitalization and pulmonary support Epidemiology Incidence login to view 2 more bullets Risk factors login to view 2 more bullets Etiology Incubation login to view 14 more bullets Transmission login to view 11 more bullets Classification SARS-CoV-2 is in the same subgenus as severe acute respiratory syndrome corona virus (SARS-CoV) Presentation Symptoms login to view 13 more bullets Physical exam login to view 3 more bullets Imaging Radiographs login to view 2 more bullets CT login to view 5 more bullets Studies Diagnostic tests login to view 9 more bullets Serum labs login to view 5 more bullets Differential COVID-19 Differential Diagnosis Virus Fever Cough Fatigue Myalgia Headache Rhinitis Sore Throat COVID-19 ↑↑↑ ↑↑↑ ↑↑↑ ↑↑ Rare ↑ ↑ Influenza ↑↑↑ ↑↑↑ ↑↑↑ ↑↑↑ ↑↑↑ ↑ ↑ Common cold Rare ↑↑ ↑ ↑ ↑↑ ↑↑↑ ↑↑↑ Treatment Medical login to view 25 more bullets Operative login to view 2 more bullets Prevention Hand hygiene login to view 2 more bullets Respiratory hygiene login to view 2 more bullets Face coverings login to view 1 more bullet Social and physical distancing login to view 1 more bullet Screening in high-risk settings login to view 2 more bullets Vaccines login to view 9 more bullets Complications Acute respiratory distress syndrome login to view 4 more bullets Pneumonia Septic shock Cardiac arrhythmia Cardiac injury Prognosis Poor Prognostic Predictors login to view 21 more bullets