Snapshot A 32-year-old woman presents to a local clinic in Nigeria. She had been working in the rainforest as part of a conservation movement and had been bitten multiple times over the past few days by mosquitos and other flying insects. Three days ago, she developed a flu-like viral illness and recently began having minor nosebleeds. She also noted that her skin looked more yellow than normal. On exam, she is jaundiced with scleral icterus. She is also noted to have hepatomegaly and gingival bleeding. Laboratory testing reveals a transaminitis and hyperbilirubinemia. She is told that she needs to be admitted for close monitoring. Introduction Classification login to view 5 more bullets Pathogenesis login to view 4 more bullets Epidemiology Incidence login to view 1 more bullet Risk factors login to view 2 more bullets Presentation Symptoms login to view 7 more bullets Physical exam login to view 8 more bullets Studies Labs login to view 6 more bullets Guaiac stool testing login to view 1 more bullet Liver biopsy login to view 3 more bullets Making the diagnosis login to view 1 more bullet Differential Dengue fever login to view 3 more bullets Chikungunya login to view 2 more bullets Treatment Conservative login to view 7 more bullets Associated conditions hemorrhagic fever Prevention Live-attenuated virus vaccine login to view 2 more bullets Complications Shock Death Prolonged weakness and fatigue Prognosis Most patients recover without complications However, in severe cases, mortality rate is up to 60%