Snapshot A 42-year-old man presents to the emergency room from the airport. He was flying home after having spent 3 weeks on a safari in Africa. He reports feeling nauseous on the flight, attributing this to motion sickness. Additionally, he developed a nosebleed on the flight, prompting him to seek medical care as soon as he landed. He reports that for the past 3 days, he has had a cough, general muscle aches, and a headache. He has also had subjective fevers and chills. On physical exam, there is dried blood in his nares and conjunctival injection. After having his blood drawn, there is also bleeding from the puncture sites. He is isolated and admitted. Introduction Classification login to view 6 more bullets Pathogenesis login to view 2 more bullets Prevention login to view 1 more bullet Epidemiology Incidence login to view 1 more bullet Risk factors login to view 3 more bullets Presentation Symptoms login to view 8 more bullets Physical exam login to view 4 more bullets Studies Labs login to view 3 more bullets Making the diagnosis login to view 1 more bullet Differential Yellow fever login to view 3 more bullets Dengue fever login to view 4 more bullets Treatment Management approach login to view 2 more bullets Conservative login to view 7 more bullets Complications Death Bacteremia Prognosis High mortality rate