Snapshot A 23-year-old man presents to a travel clinic in preparation for his trip to Yemen. He reports that his last Tdap vaccine was at age 11 and he has not received any vaccinations since then. Noting especially that diphtheria outbreaks have been documented in Yemen, his physician recommends the Td booster, which is supposed to be given at 10-year intervals. Introduction Classification login to view 5 more bullets Associated conditions login to view 3 more bullets Prevention login to view 8 more bullets Epidemiology Demographics login to view 2 more bullets ETIOLOGY Pathogenesis login to view 4 more bullets Presentation Symptoms login to view 4 more bullets Physical exam login to view 8 more bullets Studies Bacterial culture login to view 4 more bullets Making the diagnosis login to view 1 more bullet Differential Streptococcal pharyngitis login to view 2 more bullets Treatment Medical login to view 9 more bullets Complications Airway compromise from soft tissue swelling Heart failure from myocarditis Secondary bacterial infection (i.e., pneumonia) Prognosis Symptoms are insidious Mortality is higher in young children, but generally good with prompt treatment