Snapshot A 45-year-old male presents to the clinic for black stool for the past day. He reports intermittent epigastric pain that is worse with food intake for the past 4 months. The pain is described as dull, 6/10, nonradiating and improves with antacids. He reports a 5-lb. unintended weight loss but denies diarrhea, constipation, cancer history, or fevers. A physical examination is unremarkable. Introduction Clinical definition login to view 9 more bullets Associated conditions login to view 4 more bullets Epidemiology Demographics login to view 3 more bullets Risk factors login to view 4 more bullets ETIOLOGY Pathogenesis login to view 14 more bullets Presentation Symptoms login to view 9 more bullets Physical exam login to view 2 more bullets Evaluation Diagnostic testing login to view 19 more bullets Differential Gastric malignancy login to view 2 more bullets Chronic pancreatitis login to view 2 more bullets Treatment Management depends on disease etiology and severity H. pylori-induced PUD login to view 2 more bullets NSAID-induced PUD login to view 2 more bullets Bleeding ulcers login to view 3 more bullets Surgery login to view 3 more bullets Complications Bleeding Perforation login to view 1 more bullet Obstruction Malignancy