Snapshot A 52-year-old male is brought to the emergency department for recurrent severe abdominal pain. He reports 10/10, stabbing, epigastric abdominal pain that has been happening for the past 2 months intermittently. He also endorses constipation and stool that is difficult to flush. His caregiver reports a long history of alcohol abuse. A laboratory study demonstrates mildly elevated levels of amylase and lipase. Introduction Clinical definition login to view 4 more bullets Epidemiology Demographics login to view 1 more bullet ETIOLOGY Pathogenesis login to view 15 more bullets Presentation Symptoms login to view 9 more bullets Physical exam login to view 1 more bullet imaging Abdominal computed tomography (CT) with contrast login to view 2 more bullets Magnetic resonance cholangiopancreatography (MRCP) login to view 3 more bullets Endoscopic retrograde cholangiopancreatography (ERCP) login to view 1 more bullet Studies Diagnostic testing login to view 15 more bullets Differential Pancreatic cancer login to view 2 more bullets Acute pancreatitis login to view 2 more bullets Treatment Management is multipronged and is aimed to target pain management, correction of pancreatic insufficiency, and management of complications First-line login to view 5 more bullets Second-line login to view 7 more bullets Third-line login to view 3 more bullets Complications Chronic pain with addiction to analgesics Exocrine and endocrine insufficiency Pancreatic pseudocyst Ductal obstruction Increased risk of pancreatic cancer