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A 32-year-old male presents to his primary care physician because of a one month history of generalized itching, fatigue, and a recent 5 lb unintended weight loss. He is a tax accountant, with no occupational exposures, drinks alcohol occasionally on weekends, and has never smoked. His past medical history is notable for ulcerative colitis, for which he is on mesalamine therapy. On physical exam, vital signs are within normal limits. The patient is tired appearing, with no notable abnormalities; abdominal exam elicits mild tenderness to palpation in the right upper quadrant, Murphy's sign is not present. Laboratory studies show an elevated alkaline phosphatase, gamma-glutamyl-transpeptidase (GGT), and mild transaminitis. The patient is referred for endoscopic retrograde cholangiopancreatography (ERCP), which is shown in Figure A. Which of the following findings are likely present in this patient?
Computed tomography will demonstrate extensive calcification of the gall bladder
Serum anti-mitochondrial antibody titers will be elevated
Biopsy will demonstrate obliteration of intra and extrahepatic bile ducts
Serum anti-smooth muscle antibody titers will be elevated
Biopsy will demonstrate granulomatous inflammation of intrahepatic bile ducts
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