Snapshot A 50-year-old woman with a medical history of diabetes and alcoholism reports having increased shortness of breath with exertion. She has never had these symptoms before. On physical exam, she has hepatomegaly. Laboratory evaluation shows elevated liver enzymes and iron studies reveal increased ferritin and transferrin saturation level of 50%. An echocardiogram shows a mild dilated cardiomyopathy. She is scheduled for regular phlebotomy sessions. Introduction Clinical definition login to view 4 more bullets Genetics login to view 5 more bullets Epidemiology Demographics login to view 3 more bullets Etiology login to view 3 more bullets ETIOLOGY Pathogenesis login to view 2 more bullets Hereditary hemochromatosis Secondary causes login to view 1 more bullet Presentation Symptoms login to view 19 more bullets Studies Diagnostic testing login to view 14 more bullets Diagnostic criteria login to view 1 more bullet Nonalcoholic fatty liver disease (NAFLD) login to view 2 more bullets Vibrio vulnificus infection login to view 3 more bullets Treatment First-line login to view 7 more bullets Second-line login to view 3 more bullets Complications Hepatocellular carcinoma login to view 1 more bullet Cardiomyopathy login to view 1 more bullet