Snapshot A 55-year-old woman comes to the emergency department complaining of abdominal pain. She states that she has suffered intermittent nausea for 2 years. Then 3 months ago she began to notice right-sided abdominal pain. She denies vomiting, diarrhea, or constipation. She has not been to a doctor in 3 years since she moved from Peru. She has had no surgeries. She takes no medications. On physical examination, there is moderate right upper quadrant tenderness. An ultrasound shows a 5-cm cyst in the right upper lobe of the liver with an irregular, calcified wall. Introduction Clinical definition login to view 1 more bullet Epidemiology Demographics login to view 2 more bullets Risk factors login to view 3 more bullets ETIOLOGY Pathogenesis login to view 11 more bullets Presentation Symptoms login to view 7 more bullets Physical exam login to view 1 more bullet imaging Ultrasound login to view 8 more bullets Computed tomography or magnetic resonance imaging login to view 3 more bullets Studies Diagnostic testing login to view 11 more bullets Differential Simple cyst login to view 5 more bullets Cystadenoma or cystadenocarcinoma login to view 7 more bullets Treatment First-line login to view 10 more bullets Second-line login to view 7 more bullets Third-line login to view 7 more bullets Other treatments login to view 1 more bullet Complications Mass effect login to view 4 more bullets Secondary bacterial infection Cyst rupture login to view 5 more bullets