Updated: 11/11/2015

Sulfasalazine

Topic
Review Topic
0
0
Sulfalazine
  • Mechanism
    • sulfapyridine + 5-aminosalicylic acid
      • sulfapyridine is an antibiotic that surpresses B-cell function
      • 5-ASA is a COX inhibitor
    • joined molecule is split by colonic bacteria
  • Clinical use
    • ulcerative colitis
    • Crohn's disease
  • Toxicity
    • malaise/nausea
    • sulfa toxicity
    • reversible oligospermia
    • hemolysis in G6PD deficiency

References

 

Please rate topic.

Average 5.0 of 1 Ratings

Thank you for rating! Please vote below and help us build the most advanced adaptive learning platform in medicine

The complexity of this topic is appropriate for?
How important is this topic for board examinations?
How important is this topic for clinical practice?
Topic COMMENTS (0)
Private Note