Snapshot A 16-year-old girl presents to her gastroenterologist with severe, crampy, abdominal pain and intermittent nonbloody diarrhea. She has also had unexpected weight loss over the past few months. She also reports having irritating sores in her mouth. On exam, she is noted to have aphthous sores on the bucca mucosal, and skin tags around the anus. A colonoscopy a week later shows cobblestone mucosa and non-contiguous involvement of the small intestine, suggesting a diagnosis of Crohn disease. Introduction Overview login to view 3 more bullets Epidemiology Demographics login to view 1 more bullet Risk factors login to view 1 more bullet ETIOLOGY Pathogenesis login to view 3 more bullets Presentation Symptoms login to view 17 more bullets Physical exam login to view 10 more bullets Imaging Abdominal radiograph login to view 2 more bullets CT of abdomen login to view 2 more bullets Studies Serum labs login to view 5 more bullets Invasive studies login to view 10 more bullets Histology login to view 2 more bullets Differential Ulcerative colitis login to view 4 more bullets Treatment Medical login to view 27 more bullets Surgical login to view 3 more bullets Complications Fistula formation Colorectal cancer Abscesses Strictures Prognosis Unpredictable course of relapses and remissions