Snapshot A 40-year-old obese woman presents to the emergency room for pain in her right upper quadrant of her abdomen. She reports that she has had similar pain on and off for the past few weeks, but this time the pain has persisted for over an hour. She also reports nausea, vomiting, and loss of appetite. On physical exam, she has right upper quadrant pain and inspiratory arrest with deep palpation of the area. An ultrasound of that area reveals distended gallbladder with thickened gallbladder wall and gallstones. She is admitted for further management and the general surgery team is consulted for possible surgery within the next 72 hours. Introduction Clinical definition login to view 12 more bullets Epidemiology Demographics login to view 2 more bullets Risk factors login to view 10 more bullets etiology login to view 5 more bullets ETIOLOGY Pathogenesis login to view 1 more bullet Presentation Symptoms login to view 7 more bullets Physical exam login to view 11 more bullets imaging Right upper quadrant ultrasound login to view 6 more bullets Cholescintigraphy (HIDA scan) login to view 4 more bullets Computed tomography of abdomen and pelvis login to view 7 more bullets Studies Diagnostic testing login to view 4 more bullets Differential Acute pancreatitis login to view 3 more bullets DIAGNOSIS Diagnostic criteria login to view 8 more bullets Treatment First-line login to view 12 more bullets Second-line login to view 3 more bullets Complications Ascending cholangitis Gallbladder perforation Post cholecystectomy syndrome login to view 6 more bullets