Overview Snapshot A 39-year-old woman presents with two weeks of nausea, epigastric pain after eating, and weight loss. These symptoms have progressively worsened and are relieved with lying in the prone or left lateral decubitus position. Medical history is significant for poorly controlled HIV secondary to medication non-adherence. On physical exam, the patient appears underweight with a current weight of 90 lbs (40.8 kg) which decreased from her previous weight of 140 lbs (63.5 kg). An abdominal radiograph is obtained which shows dilatation of the proximal duodenum. An upper gastrointestinal series is performed which also shows proximal duodenal dilatation with delayed passage of contrast. Introduction Definition login to view 1 more bullet Epidemiology Incidence login to view 1 more bullet Demographics login to view 2 more bullets Location login to view 1 more bullet Risk factors login to view 5 more bullets ETIOLOGY Pathophysiology login to view 6 more bullets Presentation Symptoms login to view 5 more bullets Physical exam login to view 2 more bullets Imaging Plain abdominal film login to view 2 more bullets Upper gastrointestinal series login to view 2 more bullets Ultrasonography login to view 1 more bullet CT or MRI angiography (contrast enhanced) login to view 2 more bullets Differential Gastroesophageal reflux disease (GERD) Small bowel obstruction Treatment Conservative login to view 10 more bullets Operative login to view 3 more bullets Complications Complications login to view 3 more bullets Prognosis Prognostic variable login to view 1 more bullet