Snapshot A 15-year-old woman presents to urgent care with a few days of fever and sore throat. She had recently gone to an outdoor music festival and shared multiple drinks and cigarettes with friends, who had similar symptoms. She denies having a cough. She also had not taken anything for it. On physical exam, she has palatal petechiae and cervical lymphadenopathy. A peripheral blood smear showed atypical lymphocytes and a Monospot test confirmed the diagnosis. She is counseled to avoid any contact sports. Introduction Classification login to view 5 more bullets Epidemiology Incidence login to view 1 more bullet Demographics login to view 1 more bullet Risk factors login to view 8 more bullets ETIOLOGY Pathogenesis login to view 4 more bullets Associated conditions login to view 6 more bullets Presentation Symptoms login to view 4 more bullets Physical exam login to view 5 more bullets Studies Labs login to view 4 more bullets Differential Cytomegalovirus login to view 3 more bullets DIAGNOSIS Making the diagnosis login to view 2 more bullets Treatment Management approach login to view 1 more bullet Conservative login to view 6 more bullets Complications Splenic rupture Malignancy Hemolytic anemia login to view 1 more bullet Guillain-Barre syndrome Prognosis Most cases resolve