Please confirm topic selection

Are you sure you want to trigger topic in your Anconeus AI algorithm?

Please confirm action

You are done for today with this topic.

Would you like to start learning session with this topic items scheduled for future?

Updated: Dec 25 2021

Roseola Infantum

Images rash formatted.jpg
  • Snapshot
    • A 9-month old girl presents to the pediatrician for a rash on her trunk. She had a high-grade fever for 3 days, and she has been receiving ibuprofen for the fever. She has been more irritable but has been eating and having sufficient diapers. This morning, she no longer had a fever but developed a pink rash over her chest and back. On physical exam, there is a blanching, light pink rash with macules and papules on the trunk and back. She also has erythematous papules on her soft palate. Her mother is reassured that this disease is self-limited and has no complications.
  • Introduction
    • Classification
      • human herpesvirus-6 (HHV-6)
        • an enveloped, linear, double-stranded DNA virus
        • a picornavirus and enterovirus
        • transmission via respiratory secretions
        • causes roseola infantum (exanthem subitum)
    • Prevention
      • no vaccines are available
  • Epidemiology
    • Demographics
      • infants > children > adults
    • Location
      • skin
    • Risk factors
      • immunosuppression
      • transplant recipients
    • Pathogenesis
      • the virus replicates in salivary glands
      • the virus is latent in lymphocytes and monocytes
      • may contribute to tumor progression in Kaposi sarcoma and lymphoma
    • Associated conditions
      • may be associated with human herpesvirus-7
  • Presentation
    • Symptoms
      • high fever for 3 days
      • may have febrile seizures
      • no upper respiratory symptoms
      • temporally separated by rash
    • Physical exam
      • light pink, morbilliform rash that develops after the fever resolves
        • blanching
        • discrete, irregular macules and papules
        • lasts 2 days
      • Nagayama spots
        • erythematous papules on the mucosa of soft palate and uvula
  • Differential
    • Measles
      • distinguishing factor
        • cough, conjunctivitis, coryza, Koplik spots, and confluent rash excluding palms and soles
    • Rubella
      • distinguishing factor
        • postauricular lymphadenopathy with non-confluent rash that desquamates
    • Making the diagnosis
      • based on clinical presentation
  • Treatment
    • Management approach
      • mainstay of treatment is supportive care
    • Conservative
      • supportive care
        • indication
          • all patients
        • modalities
          • antipyretics
          • hydration
  • Complications
    • Seizures
  • Prognosis
    • Does not commonly recur
    • Disease is self-limited
1 of 0
1 of 1
Private Note

Attach Treatment Poll
Treatment poll is required to gain more useful feedback from members.
Please enter Question Text
Please enter at least 2 unique options
Please enter at least 2 unique options
Please enter at least 2 unique options