Snapshot A 30-year-old woman presents to the emergency room. She is a tourist from Southeast Asia and reports having a low-grade fever for several days. She also reports having arthralgias, especially in her wrists and knees. Additionally, she has a pink rash on her face and her chest. The rash appears to be spreading downward. She does not recall whether or not she had the measles, mumps, and rubella vaccine. On physical exam, she has lymphadenopathy in her postauricular and posterior cervical chains. She also has petechiae on her soft palate and uvula and a pink maculopapular rash on her face and trunk. Isolation precautions are indicated. Introduction Classification login to view 5 more bullets Prevention login to view 2 more bullets Epidemiology Incidence login to view 2 more bullets Demographics login to view 1 more bullet Risk factors login to view 2 more bullets ETIOLOGY Pathogenesis login to view 4 more bullets Associated conditions login to view 6 more bullets Presentation Symptoms login to view 4 more bullets Physical exam login to view 10 more bullets Studies Labs login to view 2 more bullets Differential Parvovirus B19 infection login to view 3 more bullets Measles login to view 3 more bullets DIAGNOSIS Making the diagnosis login to view 1 more bullet Treatment Management approach login to view 1 more bullet Conservative login to view 7 more bullets Complications Vertical transmission to fetus login to view 1 more bullet Thrombocytopenic purpura Guillain-Barre syndrome Prognosis Infection may be asymptomatic but still contagious