Snapshot A 29-year-old G1P0 woman at 30 weeks pregnancy presents to her dermatologist for a rash that started on her abdomen. She reports having significant itch with this rash. She denies any new cosmetic or medication exposures in the past few months. Her pregnancy is otherwise healthy, without complications. On physical exam, she has multiple edematous pink papules and plaques on her abdomen without scale. There is one tense intact bulla noted on the left lower abdomen. A biopsy is done and sent for histology and direct immunofluorescence, which shows a subepidermal split. Introduction Overview login to view 2 more bullets Associated conditions login to view 2 more bullets Epidemiology Incidence login to view 1 more bullet Demographics login to view 1 more bullet Risk factors login to view 2 more bullets ETIOLOGY Pathogenesis login to view 5 more bullets Presentation Symptoms login to view 3 more bullets Physical exam login to view 4 more bullets Studies Histology login to view 3 more bullets Direct immunofluorescence (DIF) login to view 1 more bullet Differential Polymorphic eruption of pregnancy login to view 3 more bullets Treatment Medical login to view 4 more bullets Complications Fetal risk login to view 1 more bullet Prognosis Good May resolve spontaneously after delivery