Snapshot A new mom brings her 4-month-old girl to the pediatrician’s office for a new red spot. She noticed a faint red spot around 1 week of age on the left cheek. Since then, it has progressed into a bigger and brighter red birth mark. It does not appear to bother the child. Physical exam reveals a 3-cm bright red and sharply demarcated raised plaque on the left cheek. The pediatrician counsels that these lesions typically resolve spontaneously, but they can consider topical β-blockers. Introduction Clinical definition login to view 10 more bullets Epidemiology Incidence login to view 1 more bullet Demographics login to view 1 more bullet Location login to view 1 more bullet Risk factors login to view 3 more bullets ETIOLOGY Pathogenesis login to view 5 more bullets Presentation Symptoms login to view 1 more bullet Physical exam login to view 7 more bullets Imaging Magnetic resonance imaging (MRI) login to view 5 more bullets Ultrasound of liver login to view 3 more bullets Studies Biopsy login to view 2 more bullets Histology login to view 1 more bullet Making the diagnosis login to view 1 more bullet Differential Port-wine stain Pyogenic granuloma Treatment Treatment and management is highly individualized based on the size of lesion, morphology, location, and age Conservative login to view 3 more bullets Medical login to view 21 more bullets Procedural login to view 3 more bullets Complications Functional impairment login to view 1 more bullet Prognosis Infantile hemangiomas often appear in the first few weeks of life login to view 1 more bullet