Snapshot A newborn infant boy is evaluated in the delivery room after delivery via cesarean section. He was born at 36 weeks of gestation to a 24-year-old G1P1 mother. On physical examination, the infant is found to have a full-thickness abdominal wall defect at the umbilicus with herniated bowel contained in a fluid-filled sac. A prenatal ultrasound from the mother's appointment at 15 weeks gestation is shown in the image. Introduction Overview login to view 5 more bullets ETIOLOGY Pathophysiology login to view 4 more bullets Associated conditions login to view 4 more bullets Epidemiology Incidence login to view 2 more bullets Demographics login to view 1 more bullet Presentation Physical exam login to view 2 more bullets Imaging Ultrasonography login to view 4 more bullets Studies Maternal serum α-fetoprotein (MSAFP) login to view 1 more bullet Differential Congenital umbilical hernia differentiating factor login to view 2 more bullets Treatment Surgical login to view 6 more bullets Complications Rupture of the omphalocele sac in utero or during delivery login to view 7 more bullets Prognosis Mortality of omphaloceles is 8 times higher relative to gastroschisis Adverse factors affecting prognosis login to view 6 more bullets