Snapshot An infant girl is brought to the pediatrician by her parents due to finding blood in her diaper. This began approximately 2-3 days prior to presentation and has not happened before. Her stools have become loose and streaked with blood. She is exclusively breastfed every 3 hours and voids approximately 10 times a day. The mother's diet consists of fish, fruits, vegetables, nuts, and milk. On physical examination, the infant is healthy-appearing and cooing. There are no anal fissures and her stool is loose with streaks of blood mixed in. Introduction Clinical definition login to view 2 more bullets Epidemiology Incidence login to view 1 more bullet Demographics login to view 1 more bullet Dietary triggers include login to view 3 more bullets ETIOLOGY Pathogenesis login to view 4 more bullets Presentation Symptoms login to view 2 more bullets Physical exam login to view 4 more bullets Differential Anal fissures login to view 1 more bullet Necrotizing enterocolitis Intussusception Enteric infection Meckel's diverticulum DIAGNOSIS Diagnostic criteria login to view 3 more bullets Treatment Conservative login to view 9 more bullets Complications Persistent food allergy login to view 1 more bullet Chronic colitis login to view 1 more bullet Prognosis Excellent because almost all infants are able to tolerate cow's milk and soy products by the time they become one year of age