Snapshot An 8-year-old girl presents to the pediatrician’s office for a recent illness. She has a sore throat and a diffuse rash that has started to peel. On physical exam, she has a diffuse sandpaper-like rash on her trunk and extremities that spares her palms and soles. The physician also notes circumoral pallor. Concerned about complications of this condition, her physician prescribes a 10-day course of amoxicillin. Introduction Clinical definition login to view 1 more bullet Epidemiology Demographics login to view 1 more bullet Risk factors login to view 1 more bullet ETIOLOGY Pathogenesis login to view 1 more bullet Associated conditions login to view 1 more bullet Presentation Symptoms login to view 2 more bullets Physical exam login to view 7 more bullets Studies Labs login to view 2 more bullets Differential Kawasaki disease login to view 5 more bullets Staphylococcal scalded skin syndrome login to view 2 more bullets DIAGNOSIS Making the diagnosis login to view 1 more bullet Treatment Management approach login to view 2 more bullets Medical login to view 15 more bullets Complications Acute rheumatic fever Rheumatic heart disease Prognosis Rash usually fades within a week Desquamation may last several weeks