Updated: 4/1/2021

Placenta Accreta

0%
Topic
Review Topic
0
0
Topic
Images
https://upload.medbullets.com/topic/121639/images/abnormalities_of_placental_implantation.jpg
https://upload.medbullets.com/topic/121639/images/placenta_accreta_ultrasound.jpg
  • Snapshot
    • A 28-year-old G3P2 female at 39 weeks of gestation is on the labor and delivery floor in active labor. The cervix is 10 centimeters dilated and preparations are made for delivery of the newborn. A male neonate is born with appropriate Apgar scores and without any perinatal complications. During placental delivery there is a lot of resistance when traction is placed on the umbilical cord. After an attempt at manual placental separation, there is profuse bleeding. Obstetric history is significant for previous cesarean delivery. She has missed a number of prenatal visits during this pregnancy.
  • Introduction
    • Overview
      • abnormal implantation of the placenta
        • chorionic villi of the placenta attach to the surface of the myometrium rather than the decidua
  • Epidemiology
    • Incidence
      • 0.17% prevalence of any placental abnormality during pregnancy
        • placenta accreta most common
          • 63% of all placental abnormalities
    • Risk factors
      • placenta previa (low-lying placenta that covers cervix) after prior C-section
      • history of uterine surgery
      • advanced maternal age
      • multiparity
      • history of manual removal of placenta
      • infertility procedures
  • ETIOLOGY
    • Pathogenesis
      • Theory of defective decidualization
        • thin, poorly formed, partial, absent or dysfunctional decidua in an area of scarring from previous uterine surgery that involved the endometrial-myometrial interface
        • allows for placental villi to attach directly to (or invade as in placenta percreta/increta) myometrium
  • Classification
    • Placenta accreta spectrum
      • placenta accreta
        • placental villi attach to myometrium (instead of decidua)
      • placenta increta
        • placental villi penetrate into the myometrium
      • placenta percreta
        • placental villi penetrate through the myometrium and attach to the uterine serosa or adjacent organs
  • Presentation
    • Symptoms
      • often asymptomatic
      • profuse life-threatening hemorrhage during attempted manual placental separation
    • Physical Exam
      • inability to fully separate placenta from uterus after delivery
  • Imaging
    • Transvaginal or transabdominal ultrasonography
      • indications
        • routine prenatal care
        • a history of cesarean delivery or other uterine surgeries
        • used for diagnosis antenatally
      • findings
        • second and third trimester
          • low anterior placenta
          • multiple irregularly shaped placental lacunae
            • placental lacunae are vascular spaces
            • “moth-eaten” appearance of placenta
          • myometrial thinning
          • placental bulge
          • disruption of bladder line
          • retroplacental space is disrupted or lost
  • Studies
    • Histology
      • placental villi attached to the myometrium in the absence of a decidual plate
      • used for diagnosis postnatally
    • Maternal serum alpha-fetoprotein
      • abnormally elevated in second trimester
  • Differential
    • Placenta increta
    • Placenta percreta
      • key distinguishing factors
        • ultrasound findings
          • placental vessels extending through myometrium into bladder or other serosa
          • a focal mass breaking through uterine serosa and extending into bladder
  • Complications
    • Massive hemorrhage
    • Death
  • Prognosis
    • 27% morbidity
      • worse with placenta percreta
    • Risk of death from sequelae of massive hemorrhage
Flashcards (0)
Cards
1 of 0
EXPERT COMMENTS (5)
Private Note