Snapshot A 25-year-old medical student with a history of severe atopic dermatitis presents to her dermatologist’s office. She recently started clinical rotations in the hospital, which she reports is stressful. She also reports to using hand sanitizer multiple times per day, which has exacerbated the atopic dermatitis on both of her hands, causing them to ooze and sting. She reports feeling so itchy at night that she is unable to sleep. Physical exam reveals large erythematous plaques on her hands and flexural surfaces including neck, antecubital fossa, and behind the knees. She is directed to use topical steroids for the body and topical tacrolimus for the face. Given the severity of her disease, her physician suggests considering a new drug, dupilumab, in the future. Introduction Clinical definition login to view 1 more bullet Genetics login to view 4 more bullets Associated conditions login to view 9 more bullets Epidemiology Prevalence login to view 2 more bullets Demographics login to view 1 more bullet Risk factors login to view 3 more bullets Etiology Pathogenesis login to view 2 more bullets Combination of genetic, dietary, and environmental causes Presentation Symptoms login to view 3 more bullets Physical exam login to view 9 more bullets Studies Labs login to view 1 more bullet Biopsy login to view 4 more bullets Making the diagnosis login to view 1 more bullet Differential Seborrheic dermatitis Contact dermatitis Ichthyosis vulgaris login to view 1 more bullet Nutritional deficiency Treatment Conservative login to view 4 more bullets Medical login to view 25 more bullets Procedural login to view 7 more bullets Complications Secondary bacterial infection Eczema herpeticum Prognosis recurrent and relapsing disease majority of childhood eczema will improve or resolve as they get older adult eczema often evolve into chronic hand eczema