Snapshot A 64-year-old female was brought to her primary care physician by her daughter due to poor appetite. When eliciting a history, you learn that the patient no longer finds joy in her hobbies, has feelings of worthlessness, is unable to sleep, and has issues concentrating. In addition to psychotherapy, the patient is prescribed sertraline. Introduction SSRIs are commonly considered first-line treatment for depression login to view 2 more bullets Treatment Drugs login to view 6 more bullets Mechanism login to view 5 more bullets Clinical use login to view 9 more bullets Toxicity login to view 16 more bullets