4.9 of 10 Ratings
A 47-year-old woman presents to the emergency department with pain in her right knee. She states that the pain started last night and rapidly worsened, prompting her presentation for care. The patient has a past medical history of rheumatoid arthritis and osteoarthritis. Her current medications include corticosteroids, infliximab, ibuprofen, and aspirin. The patient denies any recent trauma to the joint. Her temperature is 99.5°F (37.5°C), pulse is 112/min, blood pressure is 100/70 mmHg, respirations are 18/min, and oxygen saturation is 98% on room air. On physical exam, you note erythema and edema of the right knee. There is limited range of motion due to pain of the right knee. Which of the following is the best initial step in management?
Broad spectrum antibiotics
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A 3-year-old patient is brought to the emergency department by her mother due to inability to walk. The child has been limping recently and as of this morning, has refused to walk. Any attempts to make the child walk or bear weight result in crying. She was recently treated for impetigo and currently takes a vitamin D supplement. Physical exam is remarkable for an anxious appearing toddler with knee swelling, erythema, and limited range of motion due to pain. Her mother denies any recent trauma to the child's affected knee. Temperature is 103°F (39.4°C), pulse is 132/min, blood pressure is 90/50 mmHg, respirations are 18/min, and oxygen saturation is 99% on room air. Which of the following is the best initial step in management?
Synovial fluid analysis
A 55-year-old IV drug user comes into the emergency department after four days of pain in his right ankle. The patient is lethargic and unable to answer any questions about his medical history. His vitals are HR 110, T 101.5, RR 20, BP 100/60. His physical exam is notable for track marks in his toes and his right ankle is erythematous and swollen. Moving any part of the right foot creates a 10/10 pain. A radiograph revels no evidence of fractures. A Gram stain of the joint fluid aspirate demonstrates purple cocci in clusters. The fluid is yellow, opaque, with more than 70,000 cells/mm^3 (80% neutrophils). What is the most likely diagnosis?
Monosodium urate crystal formation
Salmonella infectious arthritis
Staphylococcus infectious arthritis
Borrelia infectious arthritis
A 42-year-old man with a history of gout and hypertension presents to his family physician with a complaint of increased left knee pain over the past 2 days. He also reports swelling and redness of the left knee and is unable to bear weight on that side. He denies any prior surgery or inciting trauma to the knee. His temperature is 97.0°F (36.1°C), blood pressure is 137/98 mm Hg, pulse is 80/min, respirations are 13/min, and oxygen saturation is 98% on room air. Physical examination reveals a left knee that is erythematous, swollen, warm-to-touch, and extremely tender to palpation and with attempted flexion/extension movement. His left knee range of motion is markedly reduced compared to the contralateral side. Joint aspiration of the left knee is performed with synovial fluid analysis showing turbid fluid with a leukocyte count of 95,000/mm^3, 88% neutrophils, and a low glucose. Gram stain of the synovial fluid is negative. Results from synovial fluid culture are pending. Which of the following is the best treatment regimen for this patient?
Acetaminophen and ibuprofen
Indomethacin and colchicine
Vancomycin and ceftazidime