Snapshot A 60-year-old man presents to his cardiologist for worsening shortness of breath and easy fatigability. He began developing symptoms a few months prior to presentation. His shortness of breath is most significant with exertion and he notes having swollen feet. His medical history includes hypertension, hyperlipidemia, alcohol use disorder. He currently takes hydrochlorothiazide and atorvastatin. On physical exam, an S3 heart sound and a systolic regurgitant murmur is appreciated on cardiac auscultation. An echocardiogram shows markedly dilated ventricles with a reduced ejection fraction. Summary Dilated cardiomyopathy (DCM) is the most common type of cardiomyopathy. It is caused by cardiac chamber dilation and systolic dysfunction. The condition typically presents in adults with symptoms of fatigue, dyspnea, edema, and decreased exercise tolerance. Diagnosis is made based on assessment of ventricular dilation and systolic dysfunction while ruling out other causes. Echocardiography can confirm diagnosis by visualizing ventricular changes. Treatment usually consists of addressing the underlying cause of DCM. In severe cases, operative treatment including cardioverter defibrillator, ventricular assist devices, and heart transplantation are considered. Epidemiology Incidence login to view 3 more bullets Demographics login to view 2 more bullets Location login to view 1 more bullet Risk Factors login to view 26 more bullets Etiology Pathogenesis login to view 8 more bullets Pathoanatomy login to view 3 more bullets Anatomy Cardiac walls are stretched and thinned login to view 1 more bullet Presentation Symptoms login to view 6 more bullets Physical exam login to view 9 more bullets Imaging Radiography login to view 7 more bullets Echocardiogram login to view 8 more bullets Cardiac MRI login to view 6 more bullets Studies Electrocardiography (ECG) login to view 6 more bullets Labs login to view 10 more bullets Genetics login to view 5 more bullets Diagnosis Based on LV dilation and reduce EF as demonstrated by echocardiography. Differential Restrictive cardiomyopathy login to view 3 more bullets Hypertrophic cardiomyopathy login to view 3 more bullets Treatment Goals login to view 2 more bullets Medical login to view 18 more bullets Operative login to view 11 more bullets Techniques automatic implantable cardioverter/defibrillator (AICD) login to view 13 more bullets biventricular pacemaker login to view 12 more bullets heart transplant login to view 13 more bullets Complications Heart failure Thromboembolism Prognosis Around 50% of patients die within 2 years from heart failure or arrhythmias