Snapshot A 30-year-old woman presents to her first primary care appointment. She says she experiences episodes of mild shortness of breath and palpitations; however, it does not impair her activities of daily living. She is otherwise healthy. On physical exam, a systolic murmur with a mid-systolic click is noted in the 5th intercostal space at the mid-clavicular line. Preparations are made to undergo an echocardiogram. Introduction Clinical definition login to view 1 more bullet Associated conditions login to view 4 more bullets Etiology Myxomatous degeneration login to view 1 more bullet Rheumatic fever Myocardial infarction Chordae rupture Idiopathic Pathogenesis login to view 8 more bullets Epidemiology Demographics login to view 3 more bullets Location login to view 1 more bullet Presentation Symptoms login to view 3 more bullets Physical exam login to view 6 more bullets Imaging Echocardiography login to view 5 more bullets Differential Atrial myxoma login to view 2 more bullets MurmursSystolic MurmursDiastolic MurmursAortic stenosisMitral regurgitationTricuspid regurgitationAortic regurgitationMitral stenosis Diagnosis Making the diagnosis login to view 1 more bullet Treatment Management approach login to view 2 more bullets Operative login to view 3 more bullets Complications Mitral regurgitation Chorda tendinae rupture Infective endocarditis Prognosis Progressive with age Patients are susceptible to infective endocarditis