Snapshot A 45-year-old woman presents to the emergency room for pain in her left calf. She reports flying back to the United States from Australia 2 days ago. Her flight was nonstop, making it a > 12-hour flight. She states having not worn any compression stockings and notes some swelling in the lower extremities bilaterally after the flight. She has a past medical history of hypertension and diabetes and currently takes oral contraceptive pills. Her vital signs are normal. On physical exam, her left calf is 2 cm larger in circumference than her right calf. It is also erythematous and warm with pitting edema. Her D-dimer levels are elevated. Introduction Clinical definition login to view 1 more bullet Associated conditions login to view 1 more bullet Epidemiology Incidence login to view 1 more bullet Location login to view 1 more bullet Risk factors login to view 10 more bullets Pathogenesis login to view 8 more bullets Presentation Symptoms login to view 1 more bullet Physical exam login to view 8 more bullets Imaging Compression ultrasound with Doppler login to view 5 more bullets Studies Labs login to view 4 more bullets Differential Cellulitis login to view 4 more bullets Diagnosis Making the diagnosis login to view 1 more bullet Treatment Management approach login to view 2 more bullets Conservative login to view 6 more bullets Medical login to view 21 more bullets Operative login to view 3 more bullets Complications Pulmonary embolism Phlegmasia alba dolens login to view 2 more bullets