Snapshot A 50-year-old man presents to his primary care physician for pain in his lower legs with long walks. He reports walking 10 blocks before feeling the pain and that it resolves with rest. His medical history includes hyperlipidemia, hypertension, and diabetes. His blood pressure is 145/80 mmHg, pulse is 90/min, and respirations are 18/min. On physical exam, his distal pulses are faint. His bilateral calves are dry and hairless with no peripheral ulcers. His skin is cool to the touch, especially in his feet. An ankle-brachial index is performed. Introduction Clinical definition login to view 1 more bullet Associated conditions login to view 6 more bullets Epidemiology Demographics login to view 2 more bullets Location login to view 1 more bullet Risk factors login to view 6 more bullets Etiology Pathogenesis login to view 2 more bullets Most commonly caused by atherosclerosis login to view 1 more bullet Presentation Symptoms login to view 8 more bullets Physical exam login to view 7 more bullets Imaging Doppler ultrasound login to view 4 more bullets Studies Ankle-brachial index login to view 2 more bullets Making the diagnosis login to view 1 more bullet Differential Arterial aneurysm login to view 3 more bullets Embolism (pain, pallor, paresthesias, poikilothermia, paralysis, pulselessness) login to view 5 more bullets Treatment Management approach login to view 1 more bullet Conservative login to view 6 more bullets Medical login to view 6 more bullets Operative login to view 9 more bullets Complications Osteomyelitis Loss of limb Cardiovascular event