Leading Causes of Death in the US by Age Group Listed by Age Group Leading Causes of Death in the U.S. Listed by Age Group Age Group (Years) Leading Causes of Death < 1 Congenital anomalies Short gestation Maternal pregnancy complications 1-4 Unintentional injury Congenital anomalies Malignant neoplasms 5-9 Unintentional injury Malignant neoplasms Congenital anomalies 10-14 Unintentional injury Suicide Malignant neoplasms 15-24 Unintentional injury Suicide Homicide 25-34 Unintentional injury Suicide Homicide 35-44 Unintentional injury Malignant neoplasms Heart disease 45-54 Malignant neoplasms Heart disease Unintentional injury 55-64 Malignant neoplasms Heart disease Unintentional injury 65+ Heart disease Malignant neoplasms Chronic lower respiratory disease