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A 62-year-old man with history of heart failure with preserved ejection fraction (HFpEF) and COPD presents to his cardiologist for a right heart catheterization procedure after a recent echocardiogram revealed pulmonary artery pressure (PAP) of 55 mmHg. Intraoperative administration of intravenous adenosine causes the PAP to decrease to 35 mmHg. What pharmacological therapy is most likely to provide long-term benefit for this patient?
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A 30-year-old previously healthy woman with no significant past medical history presents to the emergency department with gradually worsening shortness of breath for the past year. The patient reports worsening dyspnea on exertion, fatigue, shortness of breath, and occasional exertional chest pain. Her temperature is 97.2°F (36.2°C), blood pressure is 137/98 mm Hg, pulse is 90/min, respirations are 20/min, and oxygen saturation is 95% on room air. Physical exam is notable for bilateral clear breath sounds and an increased intensity of the P2 heart sound. A chest radiograph is seen in Figure A and an ECG is seen in Figure B which is a change from her previous sinus rhythm ECG. Which of the following is the most accurate test for this patient's condition?
Pulmonary function tests
Right-sided heart catheterization