Snapshot A 6-year-old boy presents to his pediatrician's office due to fever, frequent sputum production, and rhinorrhea. This is the 4th time this year that he has been having these symptoms, which was previously managed with bedrest and antibiotic therapy. The patient was born at term to a 29-year-old woman via spontaneous vaginal delivery. The birth was complicated by mild respiratory distress requiring oxygen supplementation for approximately 1 week. Vital signs are significant for fever, mild tachypnea, and an oxygen saturation of 94% on room air. On physical exam, there is sinus tenderness over the maxillary sinuses and crackles and wheezes on pulmonary auscultation. A radiograph of the chest is performed, which demonstrates ring shadows, tramlines, and dextrocardia. Introduction Clinical definition login to view 1 more bullet Epidemiology Incidence login to view 3 more bullets Demographics login to view 1 more bullet Etiology Autosomal recessive mutations that affect motile cilia production or function login to view 1 more bullet Pathogenesis login to view 6 more bullets Associated conditions login to view 5 more bullets Presentation Symptoms login to view 10 more bullets Physical exam login to view 4 more bullets Imaging Radiography login to view 7 more bullets Computerized tomography (CT) scan login to view 6 more bullets Differential Cystic fibrosis login to view 2 more bullets DIAGNOSIS Making the diagnosis login to view 2 more bullets Treatment Management approach login to view 1 more bullet Prognosis Long-term outcomes depend on respiratory severity Lifespan is typically expected to be normal