Snapshot A 46-year-old woman is admitted to the medical intensive care unit with severe pancreatitis. During the first 72 hours of admission, she becomes confused with increased work of breathing. Her oxygen saturation is 82% and physical exam is remarkable for tachypnea, nasal flaring, and abdominal contractions. She is placed on mechanical ventilation. A chest radiograph demonstrates bilateral infiltrates with no evidence of cardiomegaly or pleural effusions. Introduction Definition login to view 13 more bullets Etiology Pneumonia (most common risk factor) Aspiration Pulmonary contusion Acute pancreatitis Sepsis Pathogenesis login to view 10 more bullets Presentation Symptoms login to view 1 more bullet Physical exam login to view 3 more bullets Imaging Chest radiography login to view 2 more bullets Differential Diffuse alveolar hemorrhage login to view 2 more bullets Vaping-associated lung disease login to view 1 more bullet DIAGNOSIS Making the diagnosis login to view 1 more bullet Treatment Approach to treatment login to view 1 more bullet Interventional login to view 14 more bullets Prognosis Severe ARDS has the worst mortality (45%) compared to mild and moderate