Snapshot A 60-year-old woman presents to her primary care physician with pain in her hands and knees. She reports to having this pain intermittently for at least 8 months and describes it being worse in the evening. On physical exam, there is bone deformity noted on the distal and proximal interphalangeal joints, swelling of the right knee, and tenderness upon palpation of the affected joints. Introduction Clinical definition login to view 1 more bullet Epidemiology Incidence login to view 1 more bullet Demographics login to view 1 more bullet Risk factors login to view 8 more bullets Etiology Pathogenesis login to view 14 more bullets Biology and Anatomy Articular cartilage greatly decreases friction with movement and resists tension and compressive forces login to view 2 more bullets Presentation Symptoms login to view 3 more bullets Physical exam login to view 5 more bullets Imaging Radiography login to view 7 more bullets Studies Labs login to view 1 more bullet Diagnostic criteria login to view 1 more bullet Differential Rheumatoid arthritis Arthralgia Bursitis Tendonitis Treatment Conservative login to view 3 more bullets Medical login to view 5 more bullets Operative login to view 3 more bullets Complications Pain Bone deformity Functional impairment Prognosis Favorable with joint replacement