Snapshot A 27-year-old female presents with left-sided lateral knee pain. The pain initially occurred after finishing her run but now occurs at rest. The pain is of sharp quality and worsens with long distance running. On physical exam, there is tenderness upon palpation of the left lateral knee. She has a positive Noble compression test. Introduction Lateral knee pain secondary to overuse injury login to view 3 more bullets Epidemiology Runners, cyclists, and military personnel are commonly affected login to view 1 more bullet Presentation Symptom login to view 3 more bullets Physical exam login to view 3 more bullets Evaluation Clinical diagnosis Differential Patellofemoral syndrome Lateral collateral ligament sprain Treatment During acute phase login to view 3 more bullets After acute phase login to view 5 more bullets Surgical intervention login to view 1 more bullet Equipment modification login to view 2 more bullets Prevention avoid sudden increases in running mileage Prognosis patients usually respond to conservative treatment without long-term sequelae