Snapshot A 70-year-old woman presents to the emergency department for severe pain and redness of her left eye for the past day. She underwent left eye cataract surgery approximately 1 week ago. Over the past few days, her ocular pain has progressively worsened and her vision has deteriorated in her left eye. Ophthalmology was consulted and performed a dilated fundus examination, noting findings of conjunctival redness, hypopyon, and vitreous opacities. A vitreous sample is obtained and she undergoes intravitreal administration of vancomycin, ceftazidime, and voriconazole. INTRODUCTION Endophthalmitis is an inflammation of the intraocular fluids, usually due to bacterial or fungal infection. Diagnosis is made on the basis of clinical features, including eye pain, decreased visual acuity, diffuse bulbar conjunctival hyperemia, hypopyon, and signs of intraocular inflammation. Treatment consists of intravitreal injection of antimicrobials. Epidemiology incidence login to view 4 more bullets risk factors login to view 5 more bullets ETIOLOGY Pathophysiology login to view 8 more bullets Presentation Symptoms login to view 3 more bullets Physical exam login to view 6 more bullets IMAGING Ultrasound evaluation login to view 4 more bullets Studies Serum labs login to view 1 more bullet Invasive studies login to view 2 more bullets Differential Anterior uveitis login to view 3 more bullets Treatment Medical login to view 10 more bullets Surgical login to view 5 more bullets Complications Blindness Prognosis vision-threatening emergency can lead to blindness if not promptly treated visual acuity of light perception-only at presentation portends poor prognosis