Snapshot A 55-year-old woman was referred to an ophthalmologist for eye pain and photophobia. She says her symptoms are associated with visual blurriness and has noticed some "redness" in her sclera. She has a past medical history of hypertension that is adequately managed with diet and exercise and rheumatoid arthritis. She endorses previously having an oral vesicular lesion that self resolved without treatment. Physical examination is notable for ciliary flush of the left eye along with decreased corneal sensation. Slit-lamp examination with a fluorescein stain demonstrates dendritic lesions concerning for herpes simplex virus keratitis. Introduction Overview login to view 1 more bullet Epidemiology Incidence login to view 1 more bullet ETIOLOGY Pathophysiology login to view 4 more bullets Associated conditions login to view 1 more bullet Presentation Keratitis login to view 10 more bullets Conjunctivitis and blepharitis login to view 4 more bullets Studies Slit-lamp login to view 1 more bullet Differential Contact-lens associated infectious keratitis login to view 8 more bullets Herpes zoster ophthalmicus login to view 3 more bullets Treatment Medical login to view 9 more bullets Surgical login to view 3 more bullets Complications Corneal blindness Acute retinal necrosis Chorioretinitis Prognosis Can lead to corneal blindness