Snapshot A 35-year-old man is brought the emergency department following a motor vehicle accident in which his car struck a tree at high speeds. His airway, breathing, and circulation is intact and a noncontrast CT scan of the head is unremarkable. He is unconconscious but hemodynamically stabe. An MRI brain demonstrates multifocal T2-hyperintensities in the splenium of the corpus callosum. Introduction Definition login to view 2 more bullets Epidemiology incidence login to view 1 more bullet Etiology high-speed motor vehicle accidents (most common) Pathogenesis accelerating and decelerating motions that result in shearing forces to the white matter of axons, impairing neuron interconnection login to view 2 more bullets Presentation Symptoms login to view 5 more bullets Physical exam login to view 1 more bullet Imaging Noncontrast head CT login to view 5 more bullets MRI brain login to view 2 more bullets Studies Making the diagnosis login to view 2 more bullets Differential Subdural hematoma login to view 2 more bullets Subarachnoid hemorrhage login to view 3 more bullets Epidural hematoma login to view 2 more bullets Treatment Management is geared towards preventing secondary injuries and facilitating rehab login to view 1 more bullet Complications Dysautonomia