Snapshot A 45-year-old woman presents to the emergency room with persistent bleeding after a tooth extraction. She has gone through many packs of gauze without any improvement. Her past medical history includes a nephrectomy on the right side ten years ago. While dialysis was recommended two years ago, she refused. On labs, her creatinine is 6 mg/dl with normal coagulation factor levels and normal PT/PTT. She is given desmopressin (DDAVP). Introduction Overview login to view 1 more bullet Epidemiology Risk factors login to view 2 more bullets etiology Pathogenesis login to view 10 more bullets Associated conditions login to view 1 more bullet Presentation Symptoms login to view 2 more bullets Physical exam login to view 5 more bullets Studies Serum labs login to view 4 more bullets Peripheral blood smear login to view 1 more bullet Differential Glanzmann thrombasthenia login to view 2 more bullets Treatment Medical login to view 13 more bullets Complications Life-threatening gastrointestinal bleeding Prognosis Overall prognosis is poor in patients with uremia However, uremic platelet dysfunction is not the most common cause of death