Snapshot A 55-year-old man with non-Hodgkin lymphoma undergoing chemotherapy is about to get his first dose of filgrastim, a granulocyte-colony stimulating factor, for his chemotherapy-induced neutropenia. A few minutes after the dose, he starts feeling pruritus, and it was noted by the nurse that he developed urticaria over his trunk. He did not experience swelling of his lips, tongue, or throat. He is given a dose of diphenhydramine and monitored for the next few hours. His urticaria subsides, and he continues to deny any difficulty breathing or throat swelling. Introduction Drugs login to view 6 more bullets Mechanism of action login to view 4 more bullets Clinical use login to view 5 more bullets Adverse effects login to view 10 more bullets