Bifid Uvula Most common cranialfacial abnormality No clinical significance Cleft lip Can be bilateral or unilateral Due to failure of fusion of maxillary prominences Does not interfer with feeding Surgical repair Cleft palate Can be anterior or posterior Anterior due to failure of palantine shelves to fuse with primary palate Posterior due to failure of palantine shelves to fuse with nasal septum Intefers with feeding, requiring a special nipple for baby to feed Surgical repair Macroglossia Congenitally enlarged tongue seen in Down's Syndrome Gigantism congenital hypothyroidism Can be acquired in amyloidosis acromegaly Not red or inflammed like glossitis (Vit B deficiency) Treat underlying cause